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Our Pipeline

We are building a robust and diverse oncology pipeline through discovery and collaboration efforts. Our focus is on targets with novel and promising MOAs and next-generation approaches, including both small molecules and biologics.
Molecular structures shown are artistic renderings.

Zanzalintinib (XL092): TKI

An oral tyrosine kinase inhibitor (TKI) that is designed to target VEGF. MET, the TAM kinases AXL and MER, and other kinases implicated in the growth and spread of cancer.
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XB002: TF-Targeted ADC

A rationally designed, tissue factor (TF)–targeted antibody-drug conjugate (ADC) using a novel auristatin-linker payload that is designed to inhibit cell division by blocking tubulin polymerization.
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