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XL102: CDK7 Inhibitor

XL102 is a potent, selective, and orally bioavailable small molecule cyclin-dependent kinase 7 (CDK7) inhibitor, in-licensed under a collaboration agreement to supplement our drug discovery efforts.
XL102 is an inhibitor of CDK7, an important regulator of cell cycle progression and gene transcription, with overexpression observed in multiple cancers.
Phase 1 dose-escalation and expansion study of XL102 as single-agent and combination therapy in inoperable locally advanced or metastatic solid tumors
Cohort Expansions
For more information, visit
clinicaltrials.gov/NCT04726332.
This website includes information on investigational uses of compounds that have not been approved by FDA. Safety and efficacy of investigational compounds and/or investigational uses of approved products have not been established. The information presented should not be construed as a recommendation for use.
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